XB-IMG-2530
Xenbase Image ID: 2530
|
Fig. 3. RB sensory neurons are induced in both donor neural and host epidermal tissue. (A–C) The location of ectopic XHox11L2 expression (A, B) compared to the location of lysinated rhodamine dextran (LRD, C) labeling donor neural plate tissue reveals that RB induction occurs at the border of the transplanted tissue. In embryos with pigmented neural plate tissue transplanted into the ventral ectoderm of an albino host, XHox11L2 appears within the region of the graft as seen in whole mount (D, 3.2×). (E–G) Sections of this tissue reveal the tissue contributions to ectopic XHox11L2-expressing cells. (E) Endogenous XHox11L2 stains cells in the dorsal neural tube bilaterally, shown at 40×. (F–F) Some ectopic XHox11L2 expression (arrow, F and F) was found in donor cells that contained pigment granules (arrowhead, F). Host tissue lacking pigment granules also expressed ectopic XHox11L2 (G–G). Blue Hoescht staining reveals the nucleus of each cell in the field in the sectioned tissue (F′–F, G′–G). Image published in: Rossi CC et al. (2008) Copyright © 2008. Image reproduced with permission of the Publisher, Elsevier B. V.
Image source: Published Larger Image Printer Friendly View |