Xenbase Image ID: 2539

Fig. 1. Effects of citral and BMS-453 on pronephros marker genes. Embryos were incubated during gastrulation with citral (B, E) or BMS-453 (C, F) or cultured in control medium (A, D). At the late tailbud stage 33, XSMP-30 (A–C) and XPax-2 (D–F) expression was analysed by whole mount in situ hybridization. Panels D′, E′, F′ are high magnification of the pronephric tubules area of panels D, E, F, respectively. XSMP-30 expression is severely reduced in embryos treated with the chemical inhibitors (B, C). XPax-2 expression in connective tubules and nephrostomes (arrowheads in panel D′) is lost in treated embryos (E′, F′) while expression in the duct is not affected. Image published in: Cartry J et al. (2006) Copyright © 2006. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue rgn.L regucalcin, smp30, xsmp-30, xsmp30 X. laevis Throughout NF stage 33 and 34 pronephric kidney pax2.L LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. laevis Throughout NF stage 33 and 34 tail bud eye pharyngeal arch cement gland spinal cord pronephric kidney pronephric tubule pronephric nephrostome pronephric duct brain Image source: Published Larger Image Printer Friendly View

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