Xenbase Image ID: 2548

Fig. 10. Xlim-1 and XPax-8 expression at the late gastrula stage depends on RA signalling and RA induces Xlim-1 expression in absence of protein synthesis. A–H: In situ hybridization for Xlim-1 (A–D) and XPax-8 (E–H) in control embryos (A, B, E, F) or embryos incubated with BMS-453 (C, D, G, H) for 6 h since the gastrula stage 10.5 (C, G) or the neurula stage 17 (D, H). Xlim-1 and XPax-8 staining in the pronephric lineage is reduced when the inhibitor treatment is applied at gastrula stage but not at neurula stage. I–P: Embryos incubated with RA (1 μM) at the late gastrula stage 12.5 and analysed for Xlim-1 (I–N) or XPax-8 (O, P) expression by in situ hybridization 20, 40, 60 or 120 min after the onset of the treatment. Q–T: Xlim-1 expression in control embryos (Q), in embryos treated at the late gastrula stage 12.5 with CHX (R), RA (S) or RA and CHX (T). CHX was applied 30 min before the onset of the 2 h RA treatment. Image published in: Cartry J et al. (2006) Copyright © 2006. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue lhx1.L lim-1, Lim1, lim1, Xlim-1, Xlim1 X. laevis Throughout NF stage 12.5 mesoderm lateral pax8.L pax-8, XPax-8, XPax8 X. laevis Throughout NF stage 17 mesoderm pronephric mesenchyme lateral pax8.L pax-8, XPax-8, XPax8 X. laevis Throughout NF stage 12 mesoderm pronephric mesenchyme lateral Image source: Published Larger Image Printer Friendly View

Return to previous page