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XB-IMG-2560

Xenbase Image ID: 2560


Fig. 2. Functional redundancy between GATA4, 5 and 6. (A) Xenopus embryos were injected singly and in combination with GATA4, 5 and/or 6 morpholinos, harvested at stage 28 and analysed by whole mount in situ hybridisation for MLC and Nkx2.5 expression. Morphant embryos were classified into four classes: wild type (type +, light blue bar), mild down regulation of MLC or Nkx2.5 (type −, mid blue bar), strong down regulation (type −−, purple bar) and no expression (type −−−, dark blue bar). (B, C) Graphical representations of the proportion of embryos in each class.

Image published in: Peterkin T et al. (2007)

© 2007 Elsevier Inc. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives license

GeneSynonymsSpeciesStage(s)Tissue
nkx2-5.LAR2, csx, Nkx-2.5, nkx-2.5, nkx2-5-a, nkx2-5-b, nkx2.5, tinman, XNkx-2.5, XNkx2-5X. laevisThroughout NF stage 28cardiac mesoderm
heart primordium
myl2.Scmh10, mlc2, XMLC2X. laevisThroughout NF stage 28cardiac mesoderm
heart primordium

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