Xenbase Image ID: 2561

Fig. 3. Induction of cardiac precursor gene expression is unaffected in morphant Xenopus neurulae. (A) Nkx2.5 was expressed normally at stage 16/17 when GATA4, 5 or 6 were depleted individually or in combination. (B) Cryostat sections confirmed that expression of Nkx2.5 in the cardiac mesoderm (delineated by red dashed lines) was not affected. (C) Expression of Nkx2.3, which unlike Nkx2.5 is restricted to the cardiac mesoderm (D) also remained unchanged in the triple morphants, as does eHAND (E). (Red dashed lines mark the cardiac precursors, remaining stain reflects expression in the blood island mesoderm). Image published in: Peterkin T et al. (2007) © 2007 Elsevier Inc. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives license Gene Synonyms Species Stage(s) Tissue hand1.L eHand, hand-1 X. laevis Sometime during NF stage 16 to NF stage 17 mesoderm ventral blood island ventral nkx2-5.L AR2, csx, Nkx-2.5, nkx-2.5, nkx2-5-a, nkx2-5-b, nkx2.5, tinman, XNkx-2.5, XNkx2-5 X. laevis Sometime during NF stage 16 to NF stage 17 cardiac mesoderm anterior endoderm nkx2-3.S nkx-2.3, nkx2-3-a, nkx2-3-b, nkx2.3, xnkx-2.3, xnkx2-3 X. laevis Throughout unspecified stage cardiac mesoderm Image source: Published Larger Image Printer Friendly View

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