Xenbase Image ID: 26009

Fig. 6. xZFPIP knock-down prevents cell mitosis and triggers cell death in Xenopus laevis embryos. Xenopus laevis embryos are injected in one blastomere at the two-cell stage with 25–50 ng of xZFPIP MO1 or ctrl MO. Embryos are then allowed to develop until stage 12. Animal cap explants are prepared, immunostained using an α-PH3 antibody and nuclei stained with DAPI (A). Xenopus laevis embryos are injected in one blastomere at the two-cell stage with 25–50 ng of xZFPIP MO or ctrl MO and are allowed to develop until stages 20–22. The TUNEL assay performed on whole (a, b) or sectioned embryos (c, d) shows a staining in the presumptive neural region (arrows). Image published in: Laurent A et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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