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Fig. 6. Endogenous Xath5 expression is regulated by FGF signaling. Stage 28 Fzd5-XFD transgenic embryos show decreased expression of bHLH transcription factors Xath5 (B), NeuroD (D) vs. non-transgenic controls (A, C). The expression of retinal progenitor genes Rx (E–F), and Sox2 (G–H) is not affected. Retinal expression of Xer81 is inhibited in Fz5-XFD transgenic embryos (J) vs. non-transgenic controls (I).