Xenbase Image ID: 26320

Fig. 5. Fezf represses Irx genes. All embryos are dorsal views at stage 14–15. Black and red arrowheads point at the control or injected side, respectively. (A, B) In embryos injected with Fezf1 mRNA Irx1 (A) and Irx3 (B) are downregulated. (C, D) Injection of EnR-Znf-GR mRNA caused similar Irx1 downregulation in the presence of Dex (C) but not in its absence (D). (E, F) Injection of VP16-Znf-GR mRNA caused anterior Irx1 expansion in the presence of Dex (E) but not in the absence of the hormone (F). (G–J) Irx3 is also activated by VP16-Znf-GR mRNA even in the presence of cycloheximide. Image published in: Rodríguez-Seguel E et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue irx3.L irx3b, MGC131103, xiro-3, xiro3 X. laevis Sometime during NF stage 14 to NF stage 15 neural plate diencephalon irx1.L iro, irx1-a, irx1-b, Xiro, Xiro1 X. laevis Sometime during NF stage 14 to NF stage 15 neural plate diencephalon Image source: Published Larger Image Printer Friendly View

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