Xenbase Image ID: 26323

Fig. 8. Irx repress Arx. All embryos are dorsal views at stage 14–15. Black and red arrowheads point at the control or injected side, respectively. (A) In embryos injected with Irx3-MT-GR mRNA Arx is downregulated in the presence of Dex. This effect was not observed in the absence of the hormone (not shown). (B) Impairment of Irx activity caused caudal expansion of Arx. (C, D) Injection of HG-GR-E1A mRNA caused posterior Arx expansion in the presence (C) but not in the absence of the hormone (D). (E–F) This expansion also occurred in the presence of cycloheximide. Image published in: Rodríguez-Seguel E et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue arx.S arx-a, arx-b, ct121, issx, mrx29, mrx32, mrx33, mrx36, mrx38, mrx43, mrx54, mrx76, mrx87, mrxs1, prt5, xARX X. laevis Throughout NF stage 14 to NF stage 15 diencephalon pre-chordal neural plate anterior neural fold Image source: Published Larger Image Printer Friendly View

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