Xenbase Image ID: 3224

Figure 2. FGF signaling effects on endoderm and mesoderm. These embryos have been processed by in situ hybridization for expression of the indicated transcript above each column. Embryos were treated with DMSO or SU5402 from the 8- to 16-cell stage as indicated on the side. A,B: Lateral views; embryos were collected at the blastula stage, 7.5 hr post-fertilization. C-S: Gastrula stage. C-N: Blastoporal views. O,P: Lateral views with vegetal to the bottom. Q-S: Embryos were injected into one cell at the two-cell stage with the dominant-negative FGFR1 construct XFD (500 pg); the red staining is the lineage tracer n beta gal. T: Whole embryos were treated with either DMSO or SU5402, collected at the time indicated above the lanes, and analyzed by RT-PCR for expression of the indicated markers along the side. ODC was used as a loading control. Image published in: Fletcher RB and Harland RM (2008) Copyright © 2008. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue a2m.S A2Moo, Alpha2-macroglobulin, edd, endod, endodermin, LOC108695707, ovomacroglobulin X. laevis Throughout NF stage 10 upper blastopore lip marginal zone vegt.L antipodean, brat, tVegT, vegt-a, vegt-b, xombi X. laevis Throughout NF stage 9 vegetal hemisphere bix1.3.S bix1, bix4 X. laevis Throughout NF stage 10 dorsal marginal zone upper blastopore lip marginal zone sox17a.L sox17 alpha, sox17-alpha, Sox17alpha, tSox17alpha, xsox17, Xsox17-alpha, xsox17a, Xsox17alpha, xSox17alpha1, xSox17alpha2 X. laevis Throughout NF stage 10 upper blastopore lip endoderm tbxt bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury Xenopus Throughout NF stage 10 marginal zone eomes.L eomesodermin, tbr2, xeomes X. laevis Throughout NF stage 10 dorsal marginal zone fgf4.L efgf, fgf-4, fgf4-a, fgf4-b, fgfe, HBGF-4, XEFGF, Xfgf-4, Xfgf4 X. laevis Throughout NF stage 10 dorsal marginal zone marginal zone fgf8.L AIGF, FGF-8, fgf-8b, fgf8a, fgf8b, MGC79739, Xfgf-8, Xfgf8 X. laevis Throughout NF stage 10 dorsal marginal zone Image source: Published Larger Image Printer Friendly View

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