Xenbase Image ID: 33840

Figure 1. miR-430/427/302 microRNA Family Expression(A) Sequences of human and mouse miR-302a, Xenopus laevis miR-427, and zebrafish miR-430a, representative miRNAs that belong to the miR-430/427/302 family. The seed sequence is indicated in red.(B and C) Northern blot analysis of miRNA expression during differentiation of the RUES1 and RUES2 hESC lines in (B) monolayer or (C) embryoid bodies. The probes used are indicated on the right of each panel. The small nuclear RNA U2 was used as loading control. CM, MEF-conditioned medium; 2D, differentiation in two-dimensional culture.(D) Temporal expression pattern of miR-427 during early X. laevis development. The 5.8S ribosomal RNA is used as loading control.(E) Spatial expression of miR-427 in a X. laevis embryo analyzed by whole-mount in situ hybridization. The arrow indicates the dorsal lip; arrowheads indicate the neural plate border. Image published in: Rosa A et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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