XB-IMG-40321
Xenbase Image ID: 40321
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Figure 1. Expression of Xwnt8 during gastrula and early neurula stages. Embryos were assayed for expression of Xwnt8 by whole-mount in situ hybridization. In each panel, a single embryo is shown. A: Stage 11 embryo, lateral view with dorsal to the left, and a sagittal section of the embryo. Xwnt8 expression is detected in the ventral and lateral marginal zone mesoderm. B: Stage 11.5 embryo, lateral view with dorsal to the left, and a lateral to lateral section. Expression can be found close to the blastopore and in involuted mesoderm. C: Stage 12 embryo, lateral view with dorsal to the left, and a posterior view. Expression of Xwnt8 can be found in presumptive paraxial mesoderm and expression close to the blastopore is further restricted to dorsolateral positions. D: Stage 13 embryo, lateral view with anterior to the left, a posterior view of the embryo, and two transverse sections. In the section on the right top of the panel, Xwnt8 expression in presumptive hindbrain is shown, this corresponds to the anterior-most expression in the lateral view. Expression in mesoderm close to the closing blastopore is shown in the bottom right section of the panel and corresponds to expression shown in posterior view. E: Stage 17 embryo, lateral view with anterior to the left, posterior view, and a transverse section. The anterior ectodermal expression domain, the paraxial expression, and the dorsolateral expression in the mesoderm remain, while a lateral expression domain appears in the ectoderm. In the dorsal-to-ventral section, and in an enlargement on the bottom right of the panel, initiation of Xwnt8 expression in the neural tube can be found. Image published in: In der Rieden PM et al. (2010) Copyright © 2010. Image reproduced with permission of the Publisher, John Wiley & Sons.
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