Xenbase Image ID: 40630

Figure 4. Development of anterior endodermal organs is unaffected. A,B: Hex gene expression is normal in insm1 morpholino injected samples (88%, n = 8). C,D: Frp5 expression is slightly reduced, but overall the stomach appears normal (66%, n = 25). E,F: Hnf6 expression. Hnf6 is expressed in the posterior duodenum and the gall bladder. In insm1 knockdown tadpoles, expression in the gall bladder is normal, while its expression in the gut is absent (72%, n = 18). Pa, pancreas; Li, liver; GB, gall bladder. Pictures presented in control column are of uninjected embryos, but in all cases mismatch morpholino embryos (n ge 8 for each marker) gave identical results as control, with normal expression of these markers. The pancreas is outlined. Image published in: Horb LD et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue onecut1 hnf-6, hnf6, LOC108712923 X. tropicalis Throughout NF stage 35 and 36 stomach gall bladder hhex hex, tHex, XHex X. tropicalis Throughout NF stage 35 and 36 liver sfrp5 frp5, sFRP-5, sfrp5-a, sfrp5-b, XsFRP5 X. tropicalis Throughout NF stage 35 and 36 stomach Image source: Published Larger Image Printer Friendly View

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