Xenbase Image ID: 40631

Figure 5. Initial specification of the anterior endoderm is normal. A,B: Expression of ptf1a in the developing dorsal and ventral pancreatic buds was normal in insm1 knockdown tadpoles at NF35 (100%, n = 10). C,D: Expression of pdx1 in the pancreas and duodenum was unaffected (95%, n = 20). E,F: Initial expression of hnf6 in the anterior endoderm was also unaffected by the knockdown on insm1 (100%, n = 8). Pictures presented in control column are of uninjected embryos, but in all cases mismatch morpholino embryos (n = 15 for each marker) gave identical results as control, with normal expression of these markers. Image published in: Horb LD et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue ptf1a ptf1a-a, ptf1a-b, Ptf1a/p48, XPtf1a X. tropicalis Throughout NF stage 35 and 36 foregut pdx1 ipf1, pdx-1, STF-1, XlHbox-8, XlHbox8 X. tropicalis Throughout NF stage 35 and 36 foregut duodenum onecut1 hnf-6, hnf6, LOC108712923 X. tropicalis Throughout NF stage 35 and 36 endoderm foregut alimentary system cranial nerve vagus nerve trigeminal nerve facial nerve brain midbrain hindbrain midbrain-hindbrain boundary epibranchial placode Image source: Published Larger Image Printer Friendly View

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