Xenbase Image ID: 40738

Fig. 2. wnt4 overexpression induces the same phenotypes as injection of notch-ICD mRNA. (A-E) X. laevis embryos were injected as previously described. wnt4 mRNA was co-injected with beta-galactosidase mRNA to act as a lineage tracer [blue (A); red (B-E) staining on the injected side]. At stage 41, 3G8 is ectopic (white arrows) and 4A6 is reduced on the injected side (A). At stage 36, Na+K+ATPase (B) and slc5a2 (C) expression is reduced upon wnt4 overexpression and at stage 32 odf3 (D) and nephrin (E) expression is ectopic (white arrows). Asterisk denotes injected side. Image published in: Naylor RW and Jones EA (2009) Copyright © 2009. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue atp1b1.S atp1b1a, Beta1-Na/K-ATPase, Na+-K+-ATPase, β1-NaK-ATPase X. laevis Throughout NF stage 35 and 36 early proximal tubule late proximal tubule early distal tubule late distal tubule slc5a2.L X. laevis Throughout NF stage 35 and 36 early proximal tubule late proximal tubule cimap1a.L odf3 X. laevis Throughout NF stage 35 and 36 epidermis pronephric nephrostome nphs1.S nephrin X. laevis Throughout NF stage 35 and 36 glomus Image source: Published Larger Image Printer Friendly View

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