Xenbase Image ID: 41143

Fig. 3. Change in gene expression in the exocrine pancreas during metamorphosis. (A–C) In situ hybridization with PDX-1 probes. PDX-1 is expressed exclusively in islet cells in the tadpole (A) and frog pancreases (C), and at climax expression is extended to the dedifferentiated exocrine cells (B). (D–I) Notch-1 (D–F) and Hes-1 (G–I) genes are activated at climax, although low level of expression of Notch-1 and Hes-1 has been observed at premetamorphic and adult frogs. (Scale bar: 40 μm.) Image published in: Mukhi S et al. (2008) Copyright © 2008. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue pdx1.S ipf1, pdx-1, STF-1, XlHbox-8, XlHbox8 X. laevis Sometime during tadpole stage to adult frog stage islets of Langerhans pancreas pdx1.S ipf1, pdx-1, STF-1, XlHbox-8, XlHbox8 X. laevis Throughout climax stage pancreas exocrine pancreas islets of Langerhans exocrine cell notch1.L notch, notch-1, x-notch-1, xnotch, xnotch1, xotch X. laevis Throughout climax stage pancreas exocrine pancreas hes1.L hairy1, hes-1, hes1-a, hes1-b, Xhairy1 X. laevis Throughout climax stage pancreas exocrine pancreas Image source: Published Larger Image Printer Friendly View

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