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XB-IMG-41856

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Figure 2. Related Functions of BCL6 and Notch Signaling during LR Patterning(A) 40 ng BCL6 MO, 40 ng Control MO, or/and 2 ng mBCL6-GR was injected for each experiment. An arrow or a spiral indicates the orientation of the heart or the gut coiling, respectively. Ventral views are shown.(B) The normal left-specific expression of Xnr1 or Pitx2 is indicated by an arrow in the nucβ-gal-injected embryo.(C) 80 ng Notch1 MO or 80 ng Control MO was injected for each experiment. An arrow or a spiral indicates the orientation of the heart or the gut coiling, respectively. Ventral views are shown.(D and E) 150 ng Notch1 MO, 150 ng Control MO, or/and 1 ng GR-NICD RNA was injected for each experiment. The dotted line indicates the embryonic midline. The injected side is indicated by “L” (left) or “R” (right) beside the names of the injected samples. L, left; R, right; a, anterior; p, posterior.

Image published in: Sakano D et al. (2010)

Copyright © 2010. Image reproduced with permission of the Publisher, Elsevier B. V.

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