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Fig. 10. Pax3 and Pax7 do not display redundant functions in neural crest induction and development. Pax3 morphant phenotype (A) is rescued by gain of function for Pax3 (B) but not Pax7 (C). At a later stage, Pax7 does not restore melanocyte development in Pax3 morphants either (G). Conversely, Pax3 is not sufficient to rescue Pax7 depletion (D, F), in contrast to Pax7 gain of function (E). These data indicate that the two proteins do not display similar roles in neural crest induction and development. Injected side is on the right (yellow arrow). Image published in: Maczkowiak F et al. (2010) Copyright © 2010. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 16 cranial neural crest Image source: Published Larger Image Printer Friendly View

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