Xenbase Image ID: 43262

Figure 3. Developmental expression profiles and knockdown analysis of XHAPLN3 and Xhas2. A-D: Whole-mount in situ hybridization of Nkx2.5 (A), XHAPLN3 (B), Xversican (C), and Xhas2 (D). Lateral views are shown, with the anterior toward the left and dorsal side upward. The arrowhead indicates the precardiac mesoderm (PCM). E-G: The effects of depleting XHAPLN3 and Xhas2 are validated by the pattern of XcTnI expression. Normal tadpole heart structure (E, arrow). F,G: However, both XHAPLN3-morphant (F) and Xhas2-morphant (G) show no XcTnI expression. Ventral views are shown, with anterior upward. Image published in: Asashima M et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue nkx2-5.S AR2, csx, Nkx-2.5, nkx-2.5, nkx2-5-a, nkx2-5-b, nkx2.5, tinman, XNkx-2.5, XNkx2-5 X. laevis Throughout NF stage 25 cardiac mesoderm primary heart field secondary heart field hapln3.L xhapln3 X. laevis Throughout NF stage 25 mesoderm heart cardiac mesoderm primary heart field secondary heart field presomitic mesoderm otic region vcan.L chondroitin sulfate proteoglycan 2, versican, Xversican X. laevis Throughout NF stage 25 mesoderm cardiac mesoderm head region presomitic mesoderm neural tube cranial neural crest has2.S XHas2 X. laevis Throughout NF stage 25 mesoderm cardiac mesoderm presomitic mesoderm head region paraxial mesoderm Image source: Published Larger Image Printer Friendly View

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