XB-IMG-43353
Xenbase Image ID: 43353
|
Fig. 9. Effect of Cdx knockdown on endoderm development. A–C: Whole-mount in situ hybridizations to the indicated endodermal markers from neurula to tadpole stages. A,B: Show that expression of the endodermal marker genes Darmin, Vito, and Sox17b is unaffected in (A) early neurula stage 14 embryos (ventral views, anterior to the left and (B) late neurula stage 20 embryos (lateral view, anterior to the left) injected with a total of 20 ng of Cdx1, Cdx2 and Cdx4 MOs into the four vegetal hemisphere cells at the eight cell stage. C: Darmin expression is down-regulated in Cdx knockdown embryos at later stages of development. Lateral views of tail bud stage 32 (left panels) and tadpole stage 42 (right panels) embryos (anterior to the left) are shown. Image published in: Faas L and Isaacs HV (2009) Copyright © 2009 Wiley-Liss, Inc. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |