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XB-IMG-43896

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Fig. 9. Expression of wild-type Stbm elicits neural tube closure defects and failure of neural convergent extension. (A) Control embryo at mid-neurulation with closing NT. (B) Stbm-injected embryo with defective NT closure. (C) Xfd12 expression in control embryo at stage 14. (D) Xfd12 expression reveals defective neural convergent extension in a stage 14 Stbm-injected embryo. (E) Expression of Xpax3 in a control embryo. (F) Expression of Xpax3 in an XStbm injected embryo. (G) Expression of Xash3 in a control embryo. (H) Expression of Xash3 in an XStbm-injected embryos. (I) Expression of Sox2 in a control embryo. (J) Expression of Sox2 in an XStbm-injected embryos.

Image published in: Wallingford JB and Harland RM (2002)

Copyright © 2002. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

GeneSynonymsSpeciesStage(s)Tissue
foxd4l1.2.Lfoxd5.2, foxD5a, FXD12, Xfd-12, Xfd12X. laevisThroughout NF stage 14 
pax3.Scdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3X. laevisThroughout NF stage 13 to NF stage 21neural plate
ascl3.Lbhlha42, bhlha44, hash4, sgn1X. laevisThroughout NF stage 13 to NF stage 21neural plate
anterior neural tube
presumptive midbrain-hindbrain boundary
anterior placodal area
sox2.Lanop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2X. laevisThroughout NF stage 13 to NF stage 21neural plate

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