Xenbase Image ID: 44650

Figure 3. Expression patterns of XlMitf alpha on sections. A-D: Sections of embryos after whole-mount in situ hybridization. A: At stage 23, XlMitf alpha is expressed in cells located on the neural tube (A, black arrowhead). B: At stage 27, XlMitf alpha is expressed in cells located along the medial migration pathway of neural crest cells (yellow arrowhead). XlMitf alpha -positive cells shown by a black arrowhead are thought to have taken either a lateral or a ventral pathway (black arrowhead). C,D: At stage 29/30, XlMitf alpha is expressed in the RPE (black arrows) and epiphysis (white arrowheads in D). E: At stage 37/38, XlMitf alpha expression is detected in the lens (yellow arrows), although that in RPE is decreased. F,G: Serial sections of the trunk of a stage 27 embryo. XlMitf alpha -positive melanoblasts on the neural tube (black arrowhead in F) are also XlDct-positive (black arrowhead in G) in adjacent sections. XlMitf alpha expression is also detected in cells located along the medial pathway (F, yellow arrowheads). The staining in other organ cells not mentioned above, especially in the ectoderm, is background. As for stage 37/38 embryos (E), we performed in situ hybridization on sections to reduce background. BR, brain; EP, epiphysis; LE, lens; NO, notochord; NT, neural tube; RPE, retinal pigment epithelium. Image published in: Kumasaka M et al. (2004) Copyright © 2004. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue mitf.S MITF-A, mitf-a, mitf-b, mitfa X. laevis Throughout NF stage 23 neural tube mitf.S MITF-A, mitf-a, mitf-b, mitfa X. laevis Throughout NF stage 27 neural crest mitf.S MITF-A, mitf-a, mitf-b, mitfa X. laevis Throughout NF stage 29 and 30 retinal pigmented epithelium pineal gland mitf.S MITF-A, mitf-a, mitf-b, mitfa X. laevis Throughout NF stage 37 and 38 lens Image source: Published Larger Image Printer Friendly View

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