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Fig. 1. Spatiotemporal expression of podocyte genes. (A-A′) Schematics depicting the glomus (black) in whole Xenopus embryos (A) and in transverse section at low (A′) and high (A′) magnification at stage 35. (B-J′) In situ hybridization of podocyte transcription factors wt1 (B-B′), foxc2 (C-C′), tcf21 (D-D′), mafb (E-E′) and lmx1b (F-F′) and of markers of podocyte differentiation kirrel (G-G′), nphs1 (H-H′), ptpru (I-I′) and nphs2 (J-J′) at stage 35 in whole-mounts (B-J) and transverse sections (B′-J′). (K) Temporal profile of podocyte gene expression in the glomus. en, endoderm; g, pronephric glomus; lpm, lateral plate mesoderm; no, notochord; nt, neural tube; so, somites; t, pronephric tubules.