Xenbase Image ID: 45199

Fig. 6. wt1 and foxc2 regulate glomulogenesis. (A-D′′′) Uninjected control Xenopus embryos (A-A′′′) and embryos injected with wt1-MO1 (B-B′′′), foxc2-MO (C-C′′′) or with wt1-MO1 plus foxc2-MO (D-D′′′) at stage 40 were analyzed by histological staining with Hematoxylin and Eosin (H&E, A-D), immunohistochemistry for β1-Integrin (A′-D′) or Vimentin (A′′D′′), and in situ hybridization for aplnr (A′′′-D′′′). (A′-D′) Schematics of the histology, in which the glomus is highlighted in black. The arrowhead in C′ indicates enlarged capillary loops in foxc2 morphants. c, coelom; en, endoderm; lpm, lateral plate mesoderm; lu, lung bud; no, notochord; s, somites; t, tubule. Image published in: White JT et al. (2010) Copyright © 2010. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue itgb1.L Beta 1 integrin, cd29, fnrb, gpiia, itgb1-a, itgb1-b, mdf2, msk12, vla-beta, vlab X. laevis Throughout NF stage 40 podocyte pronephric kidney vim.L vim-a, vim-b, vimentin X. laevis Throughout NF stage 40 glomus pronephric kidney mesenchyme aplnr.L agtrl1, angio1, apj, apjr, aplnr-a, aplnr-b, hg11, msr, X-msr, Xangio1, Xmsr X. laevis Throughout NF stage 40 glomus pronephric kidney epithelial cell dorsal lateral plate mesoderm endothelial cell itgb1.S Beta 1 integrin, cd29, fnrb, gpiia, itgb1-a, itgb1-b, mdf2, msk12, vla-beta, vlab X. laevis Throughout NF stage 40 podocyte pronephric kidney glomus Image source: Published Larger Image Printer Friendly View

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