Xenbase Image ID: 45860

Fig. 2. In situ hybridization reveals the A/P pattern in the presumptive forebrain at stage 10+, and a greater A/P pattern in the ectoderm at stage 11.5. Embryos were analyzed by in situ hybridization (as described in Section 4). All views are dorsal, with anterior to the left. A, anterior; P, posterior. (A) Stage 10+, opl expression. (B) Stage 10+, fkh5 expression. (C) Stage 10.5, opl expression. (D) Stage 10.5, fkh5 expression. (E) Stage 10.5, otx2 expression. (F) Stage 10.5, HoxD1 expression. (G) Stage 11.5, opl expression. (H) Stage 11.5, fkh5 expression. (I) Stage 11.5, otx2 expression. (J) Stage 11.5, HoxD1 expression. (K) Diagram of anterior (A), middle (M) and posterior (P) domains at mid-gastrula. (L) Diagram of gene expression corresponding to A, M, and P domains at mid-gastrula. opl is expressed in all three domains. otx2 expression is primarily restricted to the anterior domain, with lower expression in the midline of the middle domain. fkh5 expression is seen in middle and posterior domains. HoxD1 is expressed in the posterior domain only. Image published in: Gamse JT and Sive H (2001) Copyright © 2001. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue zic1.S odd-paired-like, opl, Zic-r1, Zic-related-1 X. laevis Sometime during NF stage 10 to NF stage 11.5 dorsal ectoderm foxb1.S fkh-5, fkh5, xfkh-5 X. laevis Sometime during NF stage 10 to NF stage 11.5 ectoderm posterior otx2.S otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Sometime during NF stage 10.5 to NF stage 11.5 ectoderm hoxd1.S MGC131028, Xhox.lab, xhox.lab1, xhoxd1, xlab, Xlab-1 X. laevis Sometime during NF stage 10.5 to NF stage 11.5 ectoderm Image source: Published Larger Image Printer Friendly View

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