Xenbase Image ID: 46955

Figure 1. c-myc Expression Precedes slug Expression in Neural Crest Precursor Cells(A) Anterior and posterior view of c-myc expression in a stage 14 embryo. Strong expression is seen in the anterior neural fold (anterior) and around the closing blastopore (posterior).(B) Comparison of c-myc and pax6 expression in the anterior neural fold.(C) Northern analysis shows that c-myc is expressed both maternally and zygotically.(D) Temporal comparison of c-myc and slug expression. c-myc expression in neural folds can be detected by mid-gastrula stages (stage 11).(E) Double in situ showing blue cells expressing c-myc alone (white arrowhead) and purple cells coexpressing c-myc and slug (black arrowhead). The domain of c-myc expression is wider than the region that also expresses slug.(F) Overexpression of a dominant-negative Wnt ligand prevents c-myc expression (arrowhead). Image published in: Bellmeyer A et al. (2003) Copyright © 2003. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue myc c-myc, cmyc, myc-a, myc-b, X-cmyc, Xcmyc Xenopus Throughout NF stage 14 anterior neural fold blastopore Image source: Published Larger Image Printer Friendly View

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