Figure 7. c-Myc Depletion Prevents Formation of Cranial Sensory Ganglia(A) sox10 expression in the glia of the trigeminal, seventh (VII), ninth (IX), and tenth (X) cranial ganglia can be visualized on the control (ii), but not the injected (i), side of c-Myc-depleted embryos. E, the developing eye.(B) n-tubulin expression in the CNS neurons (white arrow) can be seen on both the control (ii) and depleted (i) side of the embryo, but n-tubulin expression in cranial sensory ganglia is seen only on the control side (ii).(C) Loss of placodal six-1 expression on the injected side (arrowhead) of c-Myc-depleted embryos (i). Expanded expression of the neural plate border marker opl (zic1) on the injected side (arrowhead) of c-Myc-depleted embryos (ii) shows that not all border cell fates have been lost in these embryos.
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