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Fig. 8. Npnt is not required for pronephros or mesonephros formation. (A, B) Specification of pronephros occurs normally as shown by pax8 WISH in both wt (left panels) and xdm (right panels) at the tailbud stage (black arrowheads; white arrowheads show the otic vesicle). (C, D) At stage 40, xdm pax8 expression in pronephros (black arrowheads) is indistinguishable from wild type (white arrowheads mark hindbrain expression). (E, F) Dissected mesonephros from metamorphosing mutant tadpoles (F) is morphologically indistinguishable from wild type (E); the anterior is to the left. Image published in: Abu-Daya A et al. (2011) © 2011 Elsevier Inc. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue pax8 pax-8, XPax-8, XPax8 X. tropicalis Throughout NF stage 28 pronephric kidney otic vesicle pronephric duct posterior neural tube pax8 pax-8, XPax-8, XPax8 X. tropicalis Throughout NF stage 40 pronephric kidney pronephric nephrostome otic vesicle hindbrain Image source: Published Larger Image Printer Friendly View

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