Xenbase Image ID: 48060

Fig. 1. Expression of Hh pathway components in whole-mount Xenopus embryos. Whole-mount in situ hybridisation on stage 41 embryos using probes as indicated. For each probe a lateral view and a dorsal view are shown. A Gli3 sense probe has been used in A,B. Expression of X-bhh and X-chh in the retina is restricted to the RPE (black arrowheads in C,E). X-chh is also expressed in the hindbrain (white arrowhead in E). In addition to a strong expression in the brain, some expression in the retina can be detected for X-shh, X-Smo, Gli2 and Gli3 (arrowheads in H,N,R,T). Although a strong expression in the brain can be detected, expression of X-Ptc-1, X-Ptc-2 and Gli1 in the retina at this stage is very weak (I-L,O-P). Anterior is towards the right. Scale bar: 300 μm. Image published in: Perron M et al. (2003) Copyright © 2003. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue ihh.S banded hedgehog, bhh, indian hedgehog, X-BHH, X-hh, Xbhh X. laevis Throughout NF stage 41 retinal pigmented epithelium eye retina dhh.L cephalic hedgehog, chh, desert hedgehog, dhh-1, dhh-a, dhh-b, x-chh, Xchh X. laevis Throughout NF stage 41 retinal pigmented epithelium hindbrain brain shh.L hedgehog, vhh-1, X-SHH, Xhh, xshh X. laevis Throughout NF stage 41 retina brain branchial arch hindbrain forebrain midbrain pineal gland mouth primordium smo.L smoothened, X-smoothened, XSmo X. laevis Throughout NF stage 41 retina brain hindbrain eye forebrain midbrain-hindbrain boundary pharyngeal arch stomodeal-hypophyseal primordium cranial ganglion gli2.S gli4 X. laevis Throughout NF stage 41 retina brain hindbrain eye forebrain midbrain-hindbrain boundary otic vesicle pharyngeal arch stomodeal-hypophyseal primordium gli3.L XGli-3, Xgli3 X. laevis Throughout NF stage 41 retina brain hindbrain eye midbrain-hindbrain boundary cranial ganglion mesoderm ptch1.S patched, patched1, Ptc-1, Ptc1, X-ptc1, XPtc1 X. laevis Throughout NF stage 41 brain hindbrain midbrain stomodeal-hypophyseal primordium midbrain-hindbrain boundary anterior neural tube pharyngeal arch ptch2.L patched 2, patched-2, ptc-2, ptc2, ptch2-a, ptch2-b, xptc 2, xptc-2 X. laevis Throughout NF stage 41 brain hindbrain heart stomodeal-hypophyseal primordium pharyngeal arch midbrain gli1.S Gli-1, X-gli1 X. laevis Throughout NF stage 41 brain hindbrain eye retina forebrain pharyngeal arch head region Image source: Published Larger Image Printer Friendly View

Return to previous page