Xenbase Image ID: 48141

Fig. 6. Tbx1 knockdown causes defects in cranial cartilages and head muscle hypoplasia. MO-injected sides are marked with *. (A) RT-PCR analysis in Tbx1 exint-MO-injected embryos. (B, B′) Alcian blue-stained cartilages from a stage 47 larva injected with Tbx1 exint-MO before and after dissection, respectively. (C) Alcian blue-stained cartilage from a stage 47 larva injected with Tbx1/pCS2+ (10 pg) together with Tbx1 exint-MO. So, subocular; Et, ethmoid-trabecular; I, infrarostral; M, Meckel's cartilage; Q, quadrate; C, ceratohyal; Bh, basihyal; B, branchial. (D–G) Skeletal muscle-specific 12/101 antibody staining in a stage 47 larva injected with Tbx1 exint-MO. Dorsal view (D), left view (E), right view (F), and ventral view (G). Two images are flipped horizontally to facilitate comparison (F, G). Lm, levator mandibulae; Eo, extraocular; Lab, levator arcuum branchialium; Im, intermandibular; QH, quadrato-hyoangularis; Oh, orbitohyoideus; Ih, interhyoid; Gh, geniohyoideus; Sr, subarcuales rectus; B, branchial. Image published in: Tazumi S et al. (2010) Copyright © 2010. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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