Xenbase Image ID: 48801

Fig. 7. ubp1-HGR converts foxi1-HGR-induced alpha-INCs into beta-INCs. (A-F) Xenopus embryos were injected at the 2-cell stage with foxi1-HGR or with both foxi1-HGR and ubp1-HGR RNA, along with mGFP RNA as a tracer. Injected embryos were treated with DEX at stage 12, fixed at stage 26, and then stained with B1 (red, upper panels) and with ae1 (blue, lower panels) antibodies. (G) pendrin-GFPtr embryos were injected with foxi1-HGR, ubp1-HGR and mGFP as tracer, and then stained with ae1 antibody (blue). (H) Based on ae1 and B1 staining, alpha-INCs and beta-INCs per field were scored under the various conditions; each field represents 196 μm2 of embryo surface. Error bars indicate ± s.d. Scale bar: 20 μm. Image published in: Quigley IK et al. (2011) Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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