Xenbase Image ID: 48877

Fig. 10. A model of the regulatory network controlling hhex transcription. The Nodal and mWnt pathways leading to activation of hhex transcription in the dorsal–anterior endoderm are shown in the green box. Repression of hhex transcription by BMP, zygotic Wnt8, and Vents are shown in the red box. Interactions mediated by secreted factors are indicated by hatched arrows, and interactions not yet known to be direct are indicated by dashed lines. The Nodal- and Wnt-responsive cis-elements are indicated in orange and blue boxes, respectively. Image published in: Rankin SA et al. (2011) Copyright © 2011. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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