XB-IMG-48995
Xenbase Image ID: 48995
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Fig. 3. xMIDs regulate epithelial morphology and organization. (A-A′) Transverse section through the neural plate of unilaterally injected xMID morphants stained with phalloidin. (A) Apical actin assembly in the morphant cells (white arrowheads) was attenuated compared with that on the control side (open arrowheads). (A′) EGFP mRNA (50 pg) was co-injected as a tracer. Dashed line indicates Mo-injected cells. (A′) Schematic illustration of A,A′ showing the non-Mo-containing cells outlined in blue and morphant cells in pink. (B-G) Quantification of cell morphological features in the superficial layer of the neural plate. Control-Mo (Cont.-Mo), n=53 cells (8 embryos); xMID-Mo, n=59 cells (7 embryos); xMID-Mo + xMID1, n=56 cells (13 embryos); xMID-Mo + xMID2, n=54 cells (9 embryos); xMID-Mo + xMID1&2, n=42 cells (10 embryos). *P<0.05, **P<0.01, ***P<0.001, compared with xMID-Mo. Image published in: Suzuki M et al. (2010) Copyright © 2010. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
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