Xenbase Image ID: 49822

Fig. 1. A transgene insertion ablates all forelimb structures. (A) Metamorphosing froglets heterozygous for an Nkx2.5FP transgene show normal forelimb development while (B) homozygous siblings lack forelimbs. (C, E) Skeletal preparation of a wild type froglet showing limb skeletal elements including the scapula (sc), humerus (hu), ulna (ul), and digits (dit); clavicle is hidden beneath the scapula. (D, F) All forelimb skeletal structures, including the scapula and clavicle, are missing in xdm froglets, but the ribs are unaffected (r1, r2, and r3). Image published in: Abu-Daya A et al. (2011) © 2011 Elsevier Inc. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

Return to previous page