Xenbase Image ID: 73891

Fig.7. Notch signaling does not regulate gastrula midline markers or 1° MFP. Shh and plvs are markers of 1° MFP ( Fig. S6). Blockade (B, E, H) and activation (C, F, I) of Notch signaling does not affect gastrula stage expression of these markers (A–F). Expression of plvs upon perturbation of Notch signaling (G–I) looks much like that of Shh (see Fig. 2), with FP expression only mildly affected (G'–I'). (G'–I') Transverse bisections of G–I. Image published in: Peyrot SM et al. (2011) Copyright © 2011. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue shh.L hedgehog, vhh-1, X-SHH, Xhh, xshh X. laevis Throughout NF stage 10.5 upper blastopore lip involuting marginal zone foxa4.L fkh1, foxa4-a, foxa4-b, FoxA4a, pintallavis, XFD-1, xfkh1, XFKHI, xkfh-1 X. laevis Throughout NF stage 11 dorsal marginal zone involuting marginal zone dorso-lateral marginal zone foxa4.L fkh1, foxa4-a, foxa4-b, FoxA4a, pintallavis, XFD-1, xfkh1, XFKHI, xkfh-1 X. laevis Throughout NF stage 14 notochord floor plate neural tube Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + dnrbpj + NF20 (in situ hybridization) fig.7.h, h^1 Expression Phenotype decreased amount foxa4.L expression in neural tube Xla Wt + canotch1 + NF20 (in situ hybridization) fig.7.i, i^1 Expression Phenotype increased amount foxa4.L expression in neural tube Larger Image Printer Friendly View

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