Xenbase Image ID: 74094

Fig. S4. Ectopic expression of WT1 expands the glomus domain and inhibits proximal tubule formation. (A-C) Embryos injected with WT1 RNA (200 pg) were subject to in situ hybridization for Pax2, Nephrin and Tbx2 at stage 32. Note that WT1 specifically impairs Pax2 expression in the pronephric tubules (arrowhead), whereas it increases Nephrin expression. Tbx2 expression is still detectable around the expanded pronephric mesoderm in the WT1-injected side of the embryo. Control, uninjected side. Image published in: Cho GS et al. (2011) Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tbx2.L ET, tbx2-a, tbx2-b, Xltbx2, xtbx2 X. laevis Throughout NF stage 32 pronephric kidney pronephric mesenchyme pronephric duct nphs1.S nephrin X. laevis Throughout NF stage 32 glomus pronephric kidney pax2.L LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. laevis Throughout NF stage 32 pronephric kidney pronephric duct pronephric tubule Image source: Published Larger Image Printer Friendly View

Return to previous page