Xenbase Image ID: 74112

Fig. 5. PPan depletion results in defects in NC induction. (A-C) To study the behavior of NCCs upon PPan MO or ITS2 MO injection, Slug, FoxD3 and Twist expression was analyzed. Slug, FoxD3 and Twist expression at stages 16/17 (A) and 20 (B) as well as FoxD3 and Twist expression at stage 23 (C) was reduced on the injected side upon PPan depletion, whereas ITS2 MO injection had little or no effect on NC specification and migration (arrows). Quantitative evaluations are given to the right. n, number of independent experiments; N, total number of embryos examined. Error bars indicate s.e.m. Image published in: Bugner V et al. (2011) Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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