Xenbase Image ID: 74268

Fig.1. The expression of the Notch receptor xotch and ligand delta1 in the precardiac mesoderm during early cardiogenesis. Embryos were examined by in situ hybridization analysis for the expression of xotch and delta1 in gastrula and early neurula embryos. Gastrula-stage whole embryos are viewed from the vegetal pole with the dorsal side located at the top of panels (A–D). The plane of the midsagittal sections of sibling embryos (A’, B’, C’, D’) is denoted by a dashed line in adjacent panels. Midsagittal sections are viewed with the animal pole at the top. Early neurula-stage embryos are dorsal views with anterior toward the top in (E, F), and anterior views with dorsal to the top in (E’, F’). In situ hybridization analysis reveals expression of the Notch receptor (xotch) and ligand (delta1) at the onset of gastrulation in the presumptive mesoderm of the marginal zone that narrows toward the dorsal side of embryos and is retained in cells migrating along the blastocoel roof (A–D’; arrow heads denote location of migrating xotch and delta1 positive cells). Once embryos have reached early neurula stages, the expression of both xotch and delta1 has become more restricted and is now expressed primarily in neural cell types (E–F’). Anterior views show that xotch and delta1 are expressed in the neural plate, but expression does not extend to the more ventrally located cardiac field at these stages (E’, F’; full arrows). Image published in: Miazga CM and McLaughlin KA (2009) Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue dll1.L delta-1, Delta-1, delta1, x-delta, X-delta-1, Xdelta-1, Xdelta1, XDelta1 X. laevis Sometime during NF stage 10.5 to NF stage 13   notch1.S notch, notch-1, x-notch-1, xnotch, xnotch1, xotch X. laevis Sometime during NF stage 10.5 to NF stage 13   Image source: Published Larger Image Printer Friendly View

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