Xenbase Image ID: 74563

Fig. 6. Effects of Ptf1a and Ptf1a-VP16 mRNA overexpression on organogenesis of liver, stomach and duodenum. (A) In situ hybridization for frp5 expression in control, Ptf1a-injected embryos and Ptf1a-VP16-injected embryos. (B) Normal expression is seen in the enlarged pancreas phenotype from Ptf1a-injected embryos, (C) whereas reduced expression is seen in the ectopic pancreas phenotype from Ptf1a-injected embryos. (D) No frp5 expression is detected in whole guts from Ptf1a- VP16-injected embryos. (E) In situ hybridization for Hex expression in Control, Ptf1a-injected embryos and Ptf1a-VP16-injected embryos. (F, G) Normal expression of Hex is detected in both enlarged and ectopic phenotypes from Ptf1a-injected embryos. (H) No Hex expression is detected in whole guts from Ptf1a- VP16-injected embryos. Image published in: Jarikji ZH et al. (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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