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XB-IMG-74569

Xenbase Image ID: 74569

Figure 5. Expression of HSP60 in regenerating WT and N1 limbs and during development Expression of HSP60 in regenerating WT and N1 limbs and during development. Gene expression in regenerating WT and N1 limbs and embryo tissue. (A-J) In situ hybridisation showing Hsp60 expression in the regeneration bud. (M-P) Unoperated limb buds illustrating Hsp60 expression during limb development. (K) In situ hybridisation showing Hsp60 expression in stage 57 hindlimb of a WT animal 2 days after amputation. (L) In situ hybridisation showing Hsp60 expression in stage 32 embryo. White arrowheads indicate approximate amputation plane, scale bar in A applies to panels A-J and scale bar in P applies to panels M-P. In limb pictures (A-K, M-P) posterior is uppermost, and distal to the left, dr = days of regeneration. In L, anterior is to the left and dorsal uppermost.

Image published in: Pearl EJ et al. (2008)

Copyright © 2008 Pearl et al; licensee BioMed Central Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

GeneSynonymsSpeciesStage(s)Tissue
hspd1.Schaperonin, cpn60, GroEL, hld4, hsp60, hsp65, spg13X. laevisThroughout NF stage 32pronephric kidney
pronephric duct
somite
trunk somite
presomitic mesoderm
tail bud
pharyngeal arch
mandibular arch
hyoid arch
branchial arch
olfactory region
lens
eye
midbrain-hindbrain boundary
hspd1.Schaperonin, cpn60, GroEL, hld4, hsp60, hsp65, spg13X. laevisSometime during NF stage 52 to NF stage 56blastema
distal mesenchyme

Image source: Published

Experiment + Assay Source Phenotypes and Disease
Xla.Tg(hsp70:nog,cryga:GFP) + hindlimb bud amputation + HS + NF53 Fig. 5 I
Expression Phenotype
decreased amount hspd1.S expression in apical mesenchyme
Xla.Tg(hsp70:nog,cryga:GFP) + hindlimb bud amputation + HS + NF53 Fig. 5 J
Expression Phenotype
decreased amount hspd1.S expression in apical mesenchyme

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