Xenbase Image ID: 74580

Figure 4. e2a and heb are expressed during early development in X. tropicalis. (A) X. tropicalis embryos were analyzed by RTCR for expression of heb and e2a, from blastula stage through early neurula. Ornithine decarboxylase (odc) was used as a loading control. (B) Vegetal endoderm explants of stage 10.5 X. tropicalis express e2a at low levels, but not the mesoderm- specific gene xbra. (C) X. tropicalis embryos were analyzed by in situ hybridization for expression of e2a and heb at early gastrula stage (stage 10.5), at early tailbud stage (stage 22), and at late tailbud stage (32). (D) Bar graphs show the percentage of each motif present in Smad2/3 target regions during gastrulation in X. tropicalis as determined by ChIP-seq. Image published in: Yoon SJ et al. (2011) Copyright © 2011. Image reproduced on with permission of the Publisher, Cold Spring Harbor Laboratory Press. This is an Open Access article. Gene Synonyms Species Stage(s) Tissue tcf3 bhlhb21, E12, e2a, itf1, tcf-3, tcfe2a, vdir, XE12, xtcf-3, xtcf3 X. tropicalis Throughout NF stage 10.5 mesoderm ectoderm tcf3 bhlhb21, E12, e2a, itf1, tcf-3, tcfe2a, vdir, XE12, xtcf-3, xtcf3 X. tropicalis Throughout NF stage 22 whole organism tcf3 bhlhb21, E12, e2a, itf1, tcf-3, tcfe2a, vdir, XE12, xtcf-3, xtcf3 X. tropicalis Throughout NF stage 32 head region mesoderm paraxial mesoderm lateral plate mesoderm chordoneural hinge hindbrain neuroectoderm pharyngeal arch pronephric duct tcf12 HEB, XE1.1 X. tropicalis Throughout NF stage 10.5 mesoderm involuting marginal zone marginal zone tcf12 HEB, XE1.1 X. tropicalis Throughout NF stage 22 lateral plate mesoderm optic vesicle hindbrain presomitic mesoderm tcf12 HEB, XE1.1 X. tropicalis Throughout NF stage 32 optic vesicle pharyngeal arch branchial arch hindbrain presomitic mesoderm Image source: Published Larger Image Printer Friendly View

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