Xenbase Image ID: 75186

FIG. 4. Expression of endogenous Pax-6 compared with that of GFP driven by the Pax-6 promoter as seen in sagittal sections of stage 32 embryos. Top row shows in situ hybridization to GFP driven off the Pax-6 promoter and bottom row shows in situ hybridization to endogenous Pax-6 mRNA. Both the transgene and the endogenous gene are expressed in the retina (A and D) but the transgene is absent from the lens (A). The transgene also shows higher expression in the telencephalon (arrow, A) but lower expression in the diencephalon (B versus E). GFP is expressed in the hindbrain (B), in a similar domain to Pax-6 (compare B to E). Both GFP and Pax-6 are expressed in the neural tube (C and F, respectively). Abbreviations: HB, hindbrain; L, lens; Di, diencephalon; NR, neural retina. Image published in: Hartley KO et al. (2001) Copyright © 2001. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue pax6.L an2, mgda, pax-6, pax6-a, pax6-b, wagr, XLPAX6, xpax6 X. laevis Throughout NF stage 32 diencephalon hindbrain eye lens placode retina neural tube Image source: Published Larger Image Printer Friendly View

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