Xenbase Image ID: 75204

Fig. 5. XBF-1 regulates the expression of X-Myt-1 and X-ngnr-1. Embryos injected with XBF-1/lacZ (A-F) and qin/lacZ (G,H) or lacZ (J) RNA and analysed for X-Myt-1 (A-E and G-J) and X-ngnr-1 expression (F). Black arrowheads connect dorsal and lateral or ventral views of the same embryos. (A,B,D,E,G,H) represent the igh dosephenotype, where X-Myt-1 is suppressed over the X-gal stained ectoderm but ectopically induced in adjacent cells. In G and J a black dotted line indicates the dorsal midline. The lateral stripe of X-Myt-1 expression (arrow in G and J) appears at a great distance from the dorsal midline in experimental embryos (G) compared to controls (J). A lateroventral view (H) of the embryo shown in (G) shows that X-Myt-1 expression formed along the boundary of the ectoderm that stained highly and uniformly with X-gal and in a punctate pattern outside it. C and F represent the low dose phenotype, where the normal expression domain of X-Myt-1 and X- ngnr-1 is greatly expanded on the injected side. The expression of X- ngnr-1 at high concentrations of XBF-1 or qin was not determined. Image published in: Bourguignon C et al. (1998) Copyright © 1998. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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