Xenbase Image ID: 75215

Fig. 1. Expression of the neuronal differentiation marker N-tubulin, in stage 16 neural plate (A), stage 27 (B,C,D) and stage 31 (E,F) tadpole Xenopus embryos. (A-D) Embryos analysed for N-tubulin expression shown in whole mount; (E,F) N-tubulin staining in sections. (A,C) Hybridised with En-2, which is a marker for the midbrain-hindbrain boundary and is shown with an arrow. (A-C) Frontal views; (D) side view of the head. Neuronal differentiation takes place at the neural plate stage and is confined to three stripes on either side of the dorsal midline. Note that the expression of N-tubulin is not detected anterior to En-2 at the neural plate stage. In contrast, N-tubulin expression can be detected in the forebrain, starting at later tadpole stages (stage 27) when it is localised to the epiphysis (black arrow), ventral postoptic diencephalon (white arrow) and olfactory placodes (white arrowhead; see also Hartenstein, 1993). At stage 31, N-tubulin expression is abundant posteriorly (F) as well as anteriorly (E). (E) A section through the forebrain (fb), including olfactory placodes (op); (F) a section through the hindbrain (hb) at the level of the otocysts (ot). Image published in: Papalopulu N and Kintner C (1996) Copyright © 1996. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 16 neural plate border neural groove tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 27 forebrain pineal gland olfactory placode diencephalon tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 31 hindbrain olfactory region Image source: Published Larger Image Printer Friendly View

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