Xenbase Image ID: 75217

Fig. 4. Blocking lateral inhibition by X-Delta-1stu does not promote early neurogenesis in response to XASH3. Animal caps expressing noggin (A) or noggin and XASH3/X-Delta-1 stu (B) do not express N-tubulin at the neural plate stage. In contrast, when animal caps that express noggin (C) or noggin and XASH3/X-Delta-1stu (D), are treated with RA at stage 9 and analysed at the same way as in A and B, they express N-tubulin. Highest levels of N-tubulin is seen in those co-injected with noggin and XASH3 /X-Delta-1stu and treated with RA (D). (C,D) Examples of sites of N-tubulin hybridisation are shown by arrowheads. In the whole embryo (E), injection of XASH3/X-Delta-1stu increases the width and density of N-tubulin cells, as previously described (Chitnis and Kintner, 1996). (E) The injected side is shown with an arrow. C, is a control embryo. Image published in: Papalopulu N and Kintner C (1996) Copyright © 1996. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Sometime during NF stage 16 to NF stage 25 neural fold neural plate Rohon-Beard neuron trigeminal placode Image source: Published Larger Image Printer Friendly View

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