XB-IMG-75439
Xenbase Image ID: 75439
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Fig. 1. AGN193109 efficiently depletes retin- oid signalling in vivo.(B) AGN treatment caused severe brain malformations. CLSM images of stage 45 tadpole brains labelled with Xen1 and 2G9 antibodies. (B) Control embryo, treated with 0.1% DMSO. (C) 10-6 M AGN treated embryos (fb: forebrain; mb: midbrain; hb: hindbrain, rn refer to rhombomere numbers). In AGN treated embryos, the number of rhombomeres was reduced to 4 or 5. Image published in: Lloret-Vilaspasa F et al. (2010) Copyright © 2010. Reproduced with permission of the Publisher, University of the Basque Country Press. Larger Image Printer Friendly View |