Xenbase Image ID: 75481

Fig. 4. Mesoderm formation is affected by lef1 depletion. Somitic boundaries of a control X. tropicalis embryo (A). The intersomitic bound- aries (white arrow heads) are affected by lef1 depletion (B). At the ventral side boundaries are lost. Myod expression in a control X. tropicalis stage 38 embryo (C) in the ventral part of somites (black arrow-head) and migrating hypaxial musculature (open arrowheads). Myod expression is downregulated in the ventral part of somites (black arrow- head) and hypaxial musculature is absent in lef1 depleted embryos (D). Control embryos stained for pax2 expression (E) in the pronephros (black arrow), pronephric duct (open arrowhead indicates junction between pronephric duct and rectal diverticulum) and rectal diverticulum. In lef1 depleted embryos (F) the caudal part of the pronephric ducts did not grow out properly and did not join the rectal diverticula, which were rudimentary (open arrowhead indicates the posterior end of an aberrant pronephric duct). Transverse section of the pronephros (G) showing pronephric tubules in a control embryo (arrows). The pronephros of lef1 depleted embryos (H) remains a single tube (arrow), with an S-shape (cf. Fig. 4F). Image published in: Roel G et al. (2009) Copyright © 2009. Reproduced with permission of the Publisher, University of the Basque Country Press. Gene Synonyms Species Stage(s) Tissue myod1 mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. tropicalis Throughout NF stage 37 and 38 somite hypaxial muscle jaw muscle pax2 LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. tropicalis Throughout NF stage 37 and 38 pronephric kidney otic vesicle spinal cord rectal diverticulum hindbrain rhombomere pronephric tubule post-anal gut late proximal tubule late distal tubule pronephric nephron Image source: Published Larger Image Printer Friendly View

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