Xenbase Image ID: 75826

Fig. 4. Runx1 expression in RB sensory neurons depends on Pax3 and Zic1. (A) Comparative expression of Pax3, Zic1 and Runx1 in stage-matched embryos indicates that the Runx1 expression domain overlaps with that of these two NPB specifiers. (B) Embryos injected with Pax3MO (50 ng) or Zic1MO (45 ng) in one blastomere at the 2-cell stage exhibit a strong reduction of Runx1 as well as N-Tub and Ngnr1 expression in RB progenitors. The injected side is on the right. In all panels embryos are viewed from the dorsal side, anterior to top. Image published in: Park BY et al. (2012) Copyright © 2012. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue runx1.L aml, aml-1, aml1, aml1 oncogene, aml1-evi-1, amlcr1, cbfa2, evi-1, LOC108709238, pebp2ab, Runx-1, Xaml, Xaml1 X. laevis Throughout NF stage 15 to NF stage 19 Rohon-Beard neuron zic1.S odd-paired-like, opl, Zic-r1, Zic-related-1 X. laevis Sometime during NF stage 15 to NF stage 19 neural plate neural plate border neural tube anterior neural ridge pax3.S cdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3 X. laevis Throughout NF stage 15 to NF stage 19 neural crest neural plate neural plate border neural tube neurog2.L atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin-related-1, neurogenin2, ngn-2, ngn2, ngnr, ngnr 1a, Ngnr-1, Ngnr1, X-ngnr-1, xngn2, Xngnr-1, XNgnr1 X. laevis Throughout NF stage 15 to NF stage 19 neural plate neural tube tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 15 to NF stage 19 Rohon-Beard neuron Image source: Published Larger Image Printer Friendly View

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