Xenbase Image ID: 75834

Fig. 4. Wnt11R is essential for neural crest specification. (A-F)Xenopus embryos were injected with the indicated MOs or RNAs and processed for in situ hybridization as described in Fig. 1. Wnt11R MO1 (A-C) and MO2 (D-F) inhibit FoxD3 (A,D) and Sox8 (B,E) but do not significantly affect Sox2 (C,F). (G)Control MO (CO MO) does not alter FoxD3. (H,I)Wnt11 and delta-N-Dsh RNAs partially suppress the inhibitory effect of Wnt11R MO1 on Sox8 (H) and FoxD3 (I). Image published in: Ossipova O and Sokol SY (2011) Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue foxd3.L fkh6, foxd3-a, foxd3-b, XFD-6, xfoxd3 X. laevis Sometime during NF stage 14 to NF stage 16 neural crest sox8.L X. laevis Sometime during NF stage 14 to NF stage 16 neural crest sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Sometime during NF stage 14 to NF stage 16 pre-chordal neural plate chordal neural plate Image source: Published Larger Image Printer Friendly View

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