XB-IMG-75986
Xenbase Image ID: 75986
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Figure S3. Loss of gene expression in the pVBI and PND in Fli1 morphants.
40 ng Fli1 MO was injected into the VMZ at the 4 cell stage, a region containing the
precursors of the pVBI and PND as well as the DLP. Runx1 and αT4globin (blood genes
not expressed in the DLP) were down regulated in Fli1 morphants (red arrows, A-D)
along with PND markers Pax2 and Pax8 (blue arrows, E-H), although the PND genes
were less sensitive to the MO than the blood genes. Partial down regulation of genes in
the aVBI results from leakage of MO from posterior to anterior at time of injection.
Image published in: Liu F et al. (2008) Copyright © 2008. Image reproduced with permission of the Publisher, Elsevier B. V.
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